Doctor Chen Li Jia Guy

CUHK Employment

Associate Professor

Head of Graduate Division

Department of Ophthalmology and Visual Sciences

The Chinese University of Hong Kong


Honorary Associate Consultant

Prince of Wales Hospital

Alice Ho Nethersole Hospital


Dr Chen is Associate Professor and Head of Graduate Division of the Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong; and Honorary Associate Consultant of the New Territory East Cluster (Prince of Wales Hospital and Alice Ho Nethersole Hospital). Dr Chen is Specialist in Ophthalmology.

Dr Chen is actively working on ophthalmic researches. His major research interest is molecular and clinical genetics of major eye diseases, including macular and retinal diseases (e.g., age-related macular degeneration and polypoidal choroidal vasculopathy, diabetic retinopathy, retinitis pigmentosa, etc.), glaucoma, myopia, and corneal dystrophy, etc. He is also working on the genetic profiling of myopia progression in children. Dr Chen and co-workers have identified a large number of new disease genes/loci, new mutations, new association profiles, and biomarkers for major eye diseases.

Dr Chen has published over 131 papers in SCI international indexed peer-reviewed journals, with an H-index of 32 (Jan 2021). He is the first or corresponding author of 50 publications. He has co-authored 1 paper in Lancet Oncology (impact factor [IF] 33.75), 7 papers in Nature Genetics (IF 27.60), 3 in Nature Communication (IF 12.12), 1 in Ocular Surface (IF 12.336), 2 in American Journal of Human Genetics (IF 10.50), 1 in PNAS (IF 9.41), 1 in Genetic Medicine (IF 8.90), 11 in Ophthalmology (IF 8.47), 3 in JAMA Ophthalmology (IF 6.19), 13 in Brit J Ophthalmol (IF 3.61), and 17 in IOVS (IF 3. 47).

Dr Chen is active in research grant application. He is the principal investigators of 7 major local (Hong Kong), National (China), and International competitive research grants, with a total amount of more than HK$6.3 million.

Dr Chen is also active in international service. He has delivered more than 30 lectures as invited speaker and chaired more than 10 sections in international conferences, mainly including the World Ophthalmology Congress, Asia-Pacific Academy of Ophthalmology (APAO) Congress, and International Symposium of Ophthalmology.

Award and Honour

2020/12 Gold Medal Award, AAPPO Academic Development Mentorship Scheme (ADMS) 2019 – 2020.

2019/11 Asia-Pacific Vitreo-retina Society (APVRS) Constable Lecture Award, 13th APVRS Congress, Shanghai, 2019.

• The APVRS Constable Lecture is presented annually at the APVRS Congress in honor of Prof Ian Constable. The Lecture is to award up and coming vitreoretinal experts for their exemplary leadership and contribution to the field.

2019/09 Distinguished Young Fellow (2019), Hong Kong Academy of Medicine.

2017/03 APAO Achievement Award 2017, the 32nd APAO Congress, Singapore.

2015/12 Gold Medal, Best Original Research of Trainee 2015, Hong Kong Academy of Medicine, Hong Kong.

2015/07 Winner of Global Research Award, 2015 Global Ophthalmology Awards Program (GOAP), From Bayer, Germany.

Research Interests

  1. Genomic studies and gene mapping of retina diseases, myopia, and glaucoma
  2. Genetics of myopia progression in children
  3. Pharmacogenetics of age-related macular degeneration
  4. Molecular genetics and epi-genetics of diabetic retinopathy, retinitis pigmentosa, uveitis, cornea dystrophies, keratoconus, and hereditary optical neuropathies
  5. Genetic prediction models for various eye diseases
  6. Genetic profiling of quantitative traits in children
  7. Investigations and territory-wide screening for eye diseases in children