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Doctor CHAN Yu-hin Eugene

Clinical Associate Professor, Department of Paediatrics, CUHK

  • +852 3513 3567
  • eugene.chan@cuhk.edu.hk

Research Theme

Paediatric Nephrology

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Biography

Dr. Eugene Chan is currently a Clinical Associate Professor at the Department of Paediatrics of the Chinese University of Hong Kong. He works at the Paediatric Nephrology Centre of Hong Kong Children’s Hospital, which is the designated, territory-wide referral centre in Hong Kong.

His research interests include nephrotic syndrome, lupus nephritis and kidney failure. Over the past few years, he has established an international collaborative network involving over 30 paediatric nephrology centres in Asia, Europe, North America and Oceania. His work has been published in top peer-reviewed nephrology journals including Kidney International and the Journal of the American Society of Nephrology.

He serves as a Co-Chair (Webinar) in the Professional Education Committee of the International Pediatric Nephrology Association and has contributed significantly to medical education in advancing global kidney care for children. He also works as an Associate Editor in Kidney International and a Section Editor in Pediatric Nephrology. Locally, he is a Council Member of the Hong Kong Paediatric Nephrology Society.

In recognition of his research and clinical contributions to the field of paediatric nephrology, he has received several international and local honours including the Young Nephrologist Award from the International Society of Nephrology, Young Investigator Award from the Asian Pacific Society of Nephrology, Young Achiever Award from the Hospital Authority, as well as Distinguished Young Fellow and Gold Medal for Best Original Research from the Hong Kong Academy of Medicine.

  • MBBS, The University of Hong Kong
  • MD, The University of Hong Kong
  • Paediatric nephrology and glomerular disease
  • Childhood nephrotic syndrome
  • Lupus nephritis
  • Kidney failure and dialysis
  • Paediatrics
  • MBBS (HK)
  • MD (HKU)
  • DCH (HK)
  • DCH (International)
  • FHKCPaed
  • FHKAM (Paed)
  • FRCPCH (UK)
  • Young Investigator Award, Asian Pacific Society of Nephrology (2024)
  • Distinguished Young Fellow, Hong Kong Academy of Medicine (2023)
  • Awardee for International Society of Nephrology – Kidney International Fellowship (2023)
  • Fellowship, International Society of Nephrology (2023)
  • Silver Medal, Best Original Research, Hong Kong Academy of Medicine (2022)
  • Best Paediatric Research of the Year, UK Kidney Week (2022)
  • Young Achiever Award, Hospital Authority (2022)
  • Young Outstanding Staff, Hong Kong Children’s Hospital (2022)
  • Gold Medal, Best Original Research, Hong Kong Academy of Medicine (2020)
  • Young Nephrologist Award, International Society of Nephrology (2019)
  • Outstanding Staff and Team Award, Hospital Authority (2017)
     
  • Associate Editor, Kidney International
  • Section Editor, Pediatric Nephrology
  • Editorial Board Member, Frontiers in Pediatrics (Pediatric Nephrology)
  • Editorial Board Member, Frontiers in Nephrology (Nephrology)

Selected Publications (*denotes first or corresponding authors)

  1. Chan EY*, Yap HK, Tullus K et al. Long-Term Efficacy and Safety of Repeated Rituximab to Maintain Remission in Idiopathic Childhood Nephrotic Syndrome: An International Study. J Am Soc Nephrol. 2022 Jun;33(6):1193-1207. doi: 10.1681/ASN.2021111472.
  2. Chan EY*, Webb H, Tullus K et al. Both the rituximab dose and maintenance immunosuppression in steroid-dependent/frequently-relapsing nephrotic syndrome have important effects on outcomes. Kidney Int. 2020 Feb;97(2):393-401. doi: 10.1016/j.kint.2019.09.033.
  3. Chan EY*, Boyer O. Levamisole in childhood idiopathic nephrotic syndrome: new promises, and advocacy for global access. Kidney Int. 2024 May;105(5):932-934. doi: 10.1016/j.kint.2024.01.030.
  4. Chan EY*, Yap DY, Ma AL et al. Renal relapse in children and adolescents with childhood-onset lupus nephritis: a 20-year study. Rheumatology (Oxford). 2023 Aug 26:kead447. doi: 10.1093/rheumatology/kead447
  5. Chan EY*, Yap DYH, Tullus K et al. The use of rituximab in childhood idiopathic nephrotic syndrome. Clin J Am Soc Nephrol. 2023 Apr 1;18(4):533-548. (Impact factor 10.671).  doi: 10.2215/CJN.08570722.
  6. Chan EY*, Leung D, Lau YL et al. Humoral and Cellular Immunogenicity and Safety of 3-Dose Inactivated COVID-19 Vaccine in Young Children Less Than 5 Years With Kidney Diseases. Kidney Int Rep. 2023 Aug 19;8(10):2177-2179. doi: 10.1016/j.ekir.2023.08.012.
  7. Chan EY*, Yap DYH, Ma AL et al. Long-term outcomes of children and adolescents with biopsy-proven childhood-onset lupus nephritis. Kidney International Reports, 2022. Kidney Int Rep. 2022 Oct 21;8(1):141-150. DOI: https://doi.org/10.1016/j.ekir.2022.
  8. Chan EY*, Ma AL, Yap DY et al.. Long-term outcomes with rituximab as add-on therapy in severe childhood-onset lupus nephritis. Pediatr Nephrol. 2023 Jun 26. doi: 10.1007/s00467-023-06025-6.
  9. Malakasioti G, Chan EY, Tullus K et al. A multicenter retrospective study of calcineurin inhibitors in nephrotic syndrome secondary to podocyte gene variants. Kidney Int. 2023 May;103(5):962-972. doi: 10.1016/j.kint.2023.02.022.
  10. Ma AL, Leung D, Chan EY et al. Antibody responses to 2 doses of mRNA COVID-19 vaccine in pediatric patients with kidney diseases. Kidney Int. 2022 May;101(5):1069-1072. (Impact factor 18.998) doi: 10.1016/j.kint.2022.01.035.
  11. Marlais M, Chan EY, Tullus K et al. Clinical Factors and Adverse Kidney Outcomes in Children With ANCA-Associated Glomerulonephritis. Am J Kidney Dis. 2022 Jul 7:S0272-6386(22)00772-7.
  12. Chan EY*, Borzych-Duzalka D, Warady et al. Colostomy in children on chronic peritoneal dialysis. Pediatr Nephrol. 2020 Jan;35(1):119-126. doi: 10.1007/s00467-019-04372-x.

 

Book chapters

  1. Chan EY*, Boyer O, K Tullus. Pediatric Glomerular Disease. Nephrology Self-assessment tool (NephSAP) 2024, an official educational material published by the American Society of Nephrology.
  2. Chan EYH*, Ma ATL, Lai WM. Development of Paediatric Nephrology in Hong Kong for “Progress in Pediatrics in Guangdong”, 2023 edition.
  3. Ma ATL, Chan EYH, Lai WM. End stage kidney disease in children. Integrated systemic nephrology, 4th edition. The University of Hong Kong
  4. Chan EYH*, Warady BA. Acquired cystic kidney disease. Pediatric Dialysis Case Studies – A practical guide to patient care. Springer, 2017. ISBN 978-3-319-55147-0