Director and Principal Investigator
Professor CHOY Kwong Wai Richard
Junior Principal Investigator
Dr. CAO Ye,
Research Assistant Professor,
Department of Paediatrics,
Department of Obstetrics and Gynaecology,
The Chinese University of Hong Kong
Dr. DONG Zirui, Elvis,
Assistant Professor
Department of Obstetrics and Gynaecology,
The Chinese University of Hong Kong
Research Team:
Research Staffs
http://www.obg.cuhk.edu.hk/our-staff/research-staff/
WONG Hoi Kin, Kenneth (Research Associate)
HO Ching Yu (Research Assistant)
TSANG Yin Ching, Kathy (Research Assistant)
TSE Ka Ching, Camellia (Research Assistant)
ZENG Xuan (Research Assistant)
CHAN Tsz Fung, Oscar (Part-time Junior Research Assistant)
Research Postgraduate Students
http://www.obg.cuhk.edu.hk/training-and-education/mphil-phd/current-students/
CHAU Hoi Kin, Matthew (PhD, Yr3)
SHI Mengmeng, Monika (PhD, Yr3)
ZHANG Yanyan (Part-time PhD, Yr2)
LI Ying, Erin (PhD, Yr2)
XUE Shuwen (PhD, Yr1)
ZHENG Yu (MPhil, Yr1)
Student | Year | Degree | Thesis Title | Academic Development |
Zhang, Yingxin | 2020 | PhD | Preimplantation Genetic Testing: Method Validation and Outcome Analysis | Technician, Prenatal diagnosis center in Shandong Provincial Hospital, China |
Zhu, Xiaofan | 2020 | PhD | Studying the Potential and Performance of Non-invasive Prenatal Testing for Genomic Disorders | Clinician, Genetics and Prenatal Diagnosis Center, The First Affiliated Hospital of Zhengzhou University, China |
Yeung, Queenie | 2019 | PhD | The Study of Non-Invasive Euploid Embryo Selection Methods in Assisted Reproductive Technology | Laboratory Supervisor, IVF Hawaii, USA |
Dong, Zi Rui, Elvis | 2017 | PhD | Whole-genome Sequencing: Method Validation, Clinical Application and Study on the Recurrent Miscarriage Couples | Research Assistant Professor, in O&G, CUHK in 2019 Postdoctoral Fellow in O&G, CUHK in 2017-2019 |
Wang, Hui Lin | 2017 | PhD | Pathogenicity Study of the Copy Number Variants Contributing to Fetal Structural Malformations | Associate Researcher, Maternal-Fetal Medicine Institute, Bao’an Maternity and Child Health Hospital Affiliated to Jinan University School of Medicine, Shenzhen, China, 2021 Senior Technician, Maternal-Fetal Medicine Institute, Bao’an Maternity and Child Health Hospital Affiliated to Jinan University School of Medicine, Shenzhen, China, 2017-2021 |
Cao, Ye | 2014 | PhD | Application of massively parallel sequencing for mutation discovery and genetic diagnosis of hereditary hearing loss in a Chinese population | Research Assistant Professor, in Paed, O&G, CUHK in 2019 Postdoctoral Fellow in Baylor College of Medicine, USA in 2017-2019 |
Tang, Tao | 2008 | PhD | Identification of microRNA profile associated with cervical cancer development | Research fellow in O&G, CUHK in 2017 |
Wong, Hoi Kin | 2008 | MPhil | Identification of coding and non-coding RNAs specific for early human retina development | Research Associate in O&G, CUHK |
Ng, Wing Chi Linda | 2007 | MPhil | Molecular characterization of human adipose tissue-derived stem cells | Research Assistant in HKU |
Collaborators
Professor MORTON, Cynthia, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA
Professor LEE, Charles, The Jackson Laboratory For Genomic Medicine, Farmington, CT, USA
Professor CHEUNG, Sau Wai, Baylor College of Medicine, Houston, TX, USA
Professor WANG, Lei, Fudan University, Shanghai, China
Professor ZHANG, Feng, Fudan University, Shanghai, China
Professor ZHU Yuanfang, Bao’an Maternity and Child Health Hospital Affiliated to Jinan University School of Medicine, Shenzhen, China
Professor WEI Hongwei, Vice-president, Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region, Nanning, China
Research Interests
- Deciphering pathogenic genomic variants by genome sequencing in:
Paediatric rare disease genetic diagnosis
Children with intellectual disability or developmental delay - Studying the contribution of rare structural variants to human disease.
- Development and validation of genome sequencing diagnostic tests.
Research Topics Include
- Development and optimization of the state-of-the-art genome sequencing approaches in comprehensively identifying various genomic variants;
- Implementation of genome sequencing approaches in genetic diagnosis for prenatal and postnatal cases;
- Comprehensive investigation of the genomic contributions in undiagnosed children and fetus with congenital abnormalities by multiple-omics approach;
- Deciphering the underlying repair mechanism of chromosomal structural rearrangements;
- Understanding of the mechanism in human early embryonic development and the potential contributions of genomic variants to early miscarriage;
- Development of non-invasive preimplantation genetic screening method utilizing cell-free DNA from embryo culture medium.
Creating an Academic Community of Young Scientists, future scholars...
